Melisa Hendrata

Melisa Hendrata
Department of Mathematics
Office Location: ST F209
Phone: 323-343-2167 Email:



I first came to CSULA as a freshman majoring in Computer Science and Mathematics. After I earned my B.S. and M.S. from CSULA, I decided to pursue my Ph.D. at University of California, Santa Barbara. While doing my graduate study, I became hooked on Mathematical Biology and in particular Computational Biomodeling as it combines applied math, computer science, and my lifelong interest in biology. I am happy to come back to CSULA to work with the students and faculty here.


  • Mathematical Biology

My research work in Mathematical Biology focuses on developing a computer simulations of biological systems to understand how biological entities, such as cells, grow and work collectively to ensure their survivals in changing environments. My current work deals with developing a multiscale agent-based model for tumor growth and its progression into cancer. The long-term goal of this research is to investigate the use of mesenchymal stem cells as therapeutic agents that promote tumor cell death. 

In the past I have also developed a bioenergetic-based computational model to study the social behavior and self-coordination in bacteria by using myxobacteria as a model system. The model simulates the swarming behavior of myxobacteria and the phase transition in their life cycle. With this model we determine essential parameters and the consequences on the mutant cells.

  • Optimization Theory

My research in the Optimization Theory focuses on Newton-type hybrid algorithms for solving a system of nonlinear equations and function minimization.




  • Ph.D. Mathematics (2009), University of California, Santa Barbara 
  • M.A. Applied Math (2008), University of California, Santa Barbara 
  • M.S. Mathematics (2004), CSULA
  • B.S. Computer Science and Mathematics (2002), CSULA